Not sure where to start? - Take the Free Fatigue recovery Quiz

Start Quiz

Take The Quiz

THE CHRONIC FATIGUE &

Burnout Recovery

PODCAST

With Anna Marsh

Welcome To The Show

Some people notice that they seem to experience stimulation and stress more intensely than others. They may feel overwhelmed in busy environments, react strongly to caffeine, or find it difficult to switch off mentally after a demanding day. Sometimes people encounter the term COMT when exploring genetic testing and begin to wonder whether this might explain their nervous system sensitivity. But conversations about COMT online can quickly become confusing — and sometimes unnecessarily alarming. In this episode, Anna explores what COMT actually does in the body, how it influences the way we process certain stress-related brain chemicals, and why some nervous systems naturally experience stimulation more strongly than others. Most importantly, we discuss why COMT is not a defect, but rather a pattern of biological sensitivity that can have both challenges and strengths.

Listen On Your Favorite Players

Explore Top Episodes

Join The Nurturing Resilience Membership

You don’t have to spend hours Googling, confused about where to start. Get the integrated approach you need—combining physical and nervous system care—to gently build capacity and recover your energy without constant crashes, flares, and setbacks.
Learn More

Episode 153: COMT – Why Some Nervous Systems Feel Everything More Intensely

Chronic Fatigue Podcast
The Chronic Fatigue and Burnout Recovery Podcast
Episode 153: COMT - Why Some Nervous Systems Feel Everything More Intensely
Loading
/

Some people notice that they seem to experience stimulation and stress more intensely than others.

They may feel overwhelmed in busy environments, react strongly to caffeine, or find it difficult to switch off mentally after a demanding day.

Sometimes people encounter the term COMT when exploring genetic testing and begin to wonder whether this might explain their nervous system sensitivity.

But conversations about COMT online can quickly become confusing — and sometimes unnecessarily alarming.

In this episode, Anna explores what COMT actually does in the body, how it influences the way we process certain stress-related brain chemicals, and why some nervous systems naturally experience stimulation more strongly than others.

Most importantly, we discuss why COMT is not a defect, but rather a pattern of biological sensitivity that can have both challenges and strengths.

Useful Links

Take the Chronic Fatigue Quiz: https://app.annamarsh.co.uk/quiz-page

Instagram: https://www.instagram.com/anna__marsh_

Work with me: https://annamarsh.co.uk/work-together/

Website: https://annamarsh.co.uk/

Join the Nurturing Resilience Subscription: https://annamarsh.co.uk/nurturing-resilience/

Previous Episodes To Explore

Back to the podcast

Take The Quiz

Ready to finally uncover your biggest roadblock when it comes to your chronic fatigue symptoms? Take the FREE Chronic Fatigue quiz below to start your fatigue recovery journey.

 
Take The Quiz

Hi, I’m Anna!

Online business owner since 2014, cat mum of two, ocean, food and chocolate lover, half mermaid, and CFS survivor!

I have more than 15 years experience in the health industry, a Masters Degree in Personalised Nutrition, and I am a fully certified  and Trauma-Trained Functional Medicine Practitioner with the Institute of Functional Medicine. 

Despite a lifelong interest in health, in 2016 CFS and mold illness turned my life upside down. 

Always the achiever, being unwell was not an option I was prepared to settle for. I committed myself to finding out what I needed to be well. It changed me as a person and as a practitioner, and it changed how I run my business. 

The fruits of my learnings are a combination of science, somatics, and neural-reprogramming used to help others overcome chronic illness and find their spark again!

Ready To Work Together?

1:1 Functional Medicine Support

This option is perfect for you if you have a complex case and you need hands-on support to get to the bottom of your symptoms. You can expect…

  • A deep dive into your health history and previous testing
  • Recommendations for Functional Testing that may help your case
  • A personalised road map to get your energy back on track
  • Feel supported every step of the way
LEARN MORE

Nurturing Resilience Membership

A self paced membership subscription for people experiencing energy limiting illnesses
  • You have been clinically or self-diagnosed CFS/ME, Fibromyalgia, PoTS, burnout or any other low energy chronic dis-ease.
  • You are looking for nervous system support alongside other healing modalities such as Functional Medicine / Nutritional Therapy.
  • You feel you have enough resourcefulness and support to benefit from a group environment.
LEARN MORE

Have A Question? Ask Away

Follow US on Instagram

Follow @anna__Marsh_

Menu

Take The Fatigue recovery Quiz

Ready to uncover what may be contributing to your chronic fatigue and start moving forward with more clarity?

TAKE THE QUIZ

A short 2-minute quiz to help you understand the factors affecting your fatigue.

Copyright © 2026 Anna Marsh. All Rights Reserved. Privacy Policy | Terms & Conditions  

Credit

Nurturing Resilience Membership

Join the nurturing Resilience Membership for just £39/month

A self paced membership subscription for people experiencing energy limiting illnesses
Learn More

Nurturing Resilience offers you the opportunity to address both, to whatever degree you need. By supporting your nervous system and physical health, you can build more resilience in your system. And with more resilience comes greater capacity to live life with less crashes, flares and setbacks!